Condyloma acuminatum occurs in perianal and genital area by infection of human papillomavirus (HPV) and appears as fairly soft verrucous papules of a cauliflower-like mass.
So far 60 HPV types have been identified. Among them, condyloma acuminatum is predominantlyassociated with HPV 6, 11 and rarely with 16, 18. HPV 16, 18 is regarded as a high-risk HPV infection because of the association of HPV 16, 18 with Bowen's
disease, cervical cancer, and anogenital cancer. In addition, a significant appearance of cervical anaplastic lesions is preceded by condyloma acuminatum and a high prevalence of cervical dysplasia has been found in female consorts of men with
genital
warts. Malignant transformation has been observed in rare incidences of condyloma acuminata on the external genitalia.
We present a case of condyloma acuminatum showing malignant transformation. The patient also has uterine cervical carcinoma. We detected HPV 16 in the lesion using polymerase chain reaction. (Kor J Dermatol 1995;33(4) : 759~763)
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